Which tumor type is classically associated with optic pathway gliomas?

• A. Ependymoma
• B. Astrocytoma
• C. Medulloblastoma
• D. Choroid plexus tumor

Answer: (B)

Optic pathway gliomas are classicly low-grade glial tumors that arise from astrocytes along the visual pathway, especially the optic nerve and chiasm. They are most commonly pilocytic astrocytomas, a subtype of astrocytoma, and are frequently seen in children with neurofibromatosis type 1. This cell of origin and typical location make astrocytoma the best answer.

Ependymomas come from ependymal cells lining the ventricles and are typically ventricular in location. Medulloblastomas originate in the cerebellum and present with posterior fossa symptoms. Choroid plexus tumors arise from the choroid plexus and often cause hydrocephalus due to CSF flow disturbance. These locations and origins are not characteristically linked to optic pathway involvement.