Which group of disorders includes PSP, MSA, and Shy-Drager syndrome?

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Multiple Choice

Which group of disorders includes PSP, MSA, and Shy-Drager syndrome?

Parkinson-plus diseases are parkinsonian disorders that come with additional neurological features beyond the classic signs of Parkinson’s disease. Progressive supranuclear palsy, multiple system atrophy (historically called Shy-Drager syndrome), and related conditions all fit this pattern because they present with parkinsonism plus other problems such as autonomic failure, gaze or balance disturbances, or cerebellar signs. This grouping is defined by that combination of symptoms, which sets them apart from idiopathic Parkinson’s disease, which mainly shows tremor, rigidity, and bradykinesia without early autonomic or gaze abnormalities. So the best label for PSP, MSA, and Shy-Drager is Parkinson-plus diseases.

Parkinson-plus diseases are parkinsonian disorders that come with additional neurological features beyond the classic signs of Parkinson’s disease. Progressive supranuclear palsy, multiple system atrophy (historically called Shy-Drager syndrome), and related conditions all fit this pattern because they present with parkinsonism plus other problems such as autonomic failure, gaze or balance disturbances, or cerebellar signs. This grouping is defined by that combination of symptoms, which sets them apart from idiopathic Parkinson’s disease, which mainly shows tremor, rigidity, and bradykinesia without early autonomic or gaze abnormalities. So the best label for PSP, MSA, and Shy-Drager is Parkinson-plus diseases.

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