Which chromosome is involved with ApoE alleles?

Prepare for the American Board of Professional Psychology (ABPP) Exam with flashcards and multiple-choice questions. Each question includes insights and explanations to help you excel. Get ready for your certification journey!

Multiple Choice

Which chromosome is involved with ApoE alleles?

ApoE alleles come from the APOE gene, which is located on chromosome 19, specifically at 19q13.2. This gene encodes apolipoprotein E, a protein key to lipid transport and cholesterol metabolism in the brain and body. The major human variants—E2, E3, and E4—arise from SNPs in this gene and have different disease associations; for example, the E4 allele is linked to higher risk of late-onset Alzheimer's disease. Because the APOE gene is on chromosome 19, that chromosome is the one involved with ApoE alleles. Chromosomes 7, 18, and 21 do not carry this gene.

ApoE alleles come from the APOE gene, which is located on chromosome 19, specifically at 19q13.2. This gene encodes apolipoprotein E, a protein key to lipid transport and cholesterol metabolism in the brain and body. The major human variants—E2, E3, and E4—arise from SNPs in this gene and have different disease associations; for example, the E4 allele is linked to higher risk of late-onset Alzheimer's disease. Because the APOE gene is on chromosome 19, that chromosome is the one involved with ApoE alleles. Chromosomes 7, 18, and 21 do not carry this gene.

More practice questions