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Multiple Choice

The nonfluent/agrammatic variant of primary progressive aphasia is best described by which features?

The core idea is the profile of nonfluent/agrammatic primary progressive aphasia. This variant is marked by speech that is effortful and halted (nonfluent), with clear problems in grammar (agrammatism) and often phonological errors. Despite these language production difficulties, comprehension is relatively preserved, especially for single words and simple sentences, and repetition tends to be relatively preserved early on. This combination—nonfluency with grammar and phonology errors, plus preserved understanding and repetition—best fits nfPPA. The other descriptions don’t match nfPPA as closely. Fluent, well-formed speech describes other PPA variants or typical early stages of non-language disorders. Fluent speech with paraphasias and impaired comprehension points toward a fluent aphasia profile (not nfPPA). Severe visuospatial impairment suggests a non-language syndrome such as posterior cortical atrophy, not nfPPA.

The core idea is the profile of nonfluent/agrammatic primary progressive aphasia. This variant is marked by speech that is effortful and halted (nonfluent), with clear problems in grammar (agrammatism) and often phonological errors. Despite these language production difficulties, comprehension is relatively preserved, especially for single words and simple sentences, and repetition tends to be relatively preserved early on. This combination—nonfluency with grammar and phonology errors, plus preserved understanding and repetition—best fits nfPPA.

The other descriptions don’t match nfPPA as closely. Fluent, well-formed speech describes other PPA variants or typical early stages of non-language disorders. Fluent speech with paraphasias and impaired comprehension points toward a fluent aphasia profile (not nfPPA). Severe visuospatial impairment suggests a non-language syndrome such as posterior cortical atrophy, not nfPPA.