Prader-Willi syndrome is characterized by hypotonia in infancy and later obesity due to hyperphagia. Which of the following describes it?

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Multiple Choice

Prader-Willi syndrome is characterized by hypotonia in infancy and later obesity due to hyperphagia. Which of the following describes it?

Prader-Willi syndrome centers on hypothalamic dysregulation that presents first as prominent low muscle tone in infancy and then drives an insatiable appetite, leading to obesity as the child grows. The option that best describes this pattern is obesity with hypotonia because it directly reflects both hallmark phases: the initial hypotonia and the subsequent obesity from hyperphagia. Hyperactivity isn’t a defining feature, puberty is typically delayed or incomplete due to hypogonadism, and while short stature can occur, it doesn’t capture the key progression as clearly as the combination of obesity with hypotonia.

Prader-Willi syndrome centers on hypothalamic dysregulation that presents first as prominent low muscle tone in infancy and then drives an insatiable appetite, leading to obesity as the child grows. The option that best describes this pattern is obesity with hypotonia because it directly reflects both hallmark phases: the initial hypotonia and the subsequent obesity from hyperphagia. Hyperactivity isn’t a defining feature, puberty is typically delayed or incomplete due to hypogonadism, and while short stature can occur, it doesn’t capture the key progression as clearly as the combination of obesity with hypotonia.

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