Alien limb syndrome is reported to occur with corticobasal degeneration. Which option reflects this association?

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Alien limb syndrome arises when the brain’s networks that plan and monitor movement become disrupted, especially in the parietal-premotor regions that integrate intention, action, and sensory feedback. In corticobasal degeneration, there is asymmetric involvement of those cortical motor–sensory areas, leading to apraxia and an alien limb that acts seemingly on its own and may resist the person’s commands. This combination—unilateral, involuntary, purposeful movements with a sense of estrangement from the limb—is a characteristic feature of corticobasal degeneration. The other conditions listed do not typically present with this distinctive limb phenomenon: PSP mainly involves eye movements and axial rigidity, Alzheimer's centers on memory with different atrophy patterns, and a PCA stroke would cause focal deficits rather than the persistent, involuntary limb actions seen in CBD.