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Multiple Choice

Abnormal stiffening and extension of the neck is one of the probable signs of which disease?

Abnormal stiffening and extension of the neck points to progressive supranuclear palsy, a parkinsonian syndrome with strong axial involvement. In PSP, rigidity and dystonic posturing of the neck and trunk are prominent, often producing a fixed, extended neck (retrocollis). This axial rigidity contrasts with the patterns seen in other diseases: Alzheimer's disease is mainly cognitive, Huntington's disease features chorea and psychiatric symptoms, and Parkinson's disease typically has tremor and bradykinesia with a better response to dopaminergic therapy, without the distinctive neck extension seen in PSP. Thus, the neck posture described best fits progressive supranuclear palsy.

Abnormal stiffening and extension of the neck points to progressive supranuclear palsy, a parkinsonian syndrome with strong axial involvement. In PSP, rigidity and dystonic posturing of the neck and trunk are prominent, often producing a fixed, extended neck (retrocollis). This axial rigidity contrasts with the patterns seen in other diseases: Alzheimer's disease is mainly cognitive, Huntington's disease features chorea and psychiatric symptoms, and Parkinson's disease typically has tremor and bradykinesia with a better response to dopaminergic therapy, without the distinctive neck extension seen in PSP. Thus, the neck posture described best fits progressive supranuclear palsy.